Doctors Finally Understand Why Obesity Causes Diabetes

Although it has long been known there is a connection between obesity and Type II diabetes, doctors did not understand the mechanisms. At Monash University, a research team led by Associate Professor Matthew Watt, has finally found the answer. Apparently, fat cells release a protien called PEDF (pigment epithelium-derived factor). When this protien is released in the bloodstream, it causes the muscles and liver to become desensitized to insulin. Consequently, the pancrease has to produce more insulin to lower the blood glucose levels and becomes overworked. The more fat a person becomes, the less sensitive to insulin they become. However, the research also showed when PEDF was blocked, individuals becams senstive to the insulin again.